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Why Does Your Injection Site Itch?



What Causes Your Injection Site To Itch?

You may have itching at the injection site for several reasons. We’ll cover a few of the most common causes below.

Injection Site Reaction

When you sustain an injury, your body will quickly begin healing. This can happen with internal injuries like strained muscles or external injuries like cuts. If the injury is external, your skin will need to heal. As your skin heals, there can be sensation changes. You could have numbness, tingling, or itching near your injury. The needle for your injections can cause a similar response. The skin around your injection site may be red or itchy as you heal. This is a normal bodily reaction and will clear up in a few days. 

Immune Reaction

You may have redness, swelling, itching, soreness, or burning at the site of your injections. If you experience these, you may be having an immune reaction to the medicine. Similar to an allergic reaction, an immune reaction is usually less severe. What if you develop itching paired with burning, swelling, redness, or soreness after an injection for several weeks or months? An immune reaction is most common as you increase your dosage with some medications.

Allergic Reaction

A more serious cause of itching could be an allergic reaction. You’ll probably have other symptoms too, so don’t worry if itching is your only complaint. Call your healthcare provider immediately if you notice any of the following symptoms:

  • Muscles aches

  • Fever

  • Severe pain or blistering at the injection site

  • Dizziness

  • Nausea or vomiting

  • Hives or skin rash

 Call 911 if you have any problems breathing or experience swelling of your lips, tongue, or throat. These are signs of a severe allergic reaction. 

Tips To Ease Injection Site Itching

It’s normal to see some irritation or itching from your injections. An itchy injection site can be irritating, but we have some tips to help minimize the effect.  

  • Applying a cold compress or a cool, sanitary washcloth can help ease the itch. This one gets bonus points because it can also help with soreness and redness.

  • Try a gentle cream or moisturizer to ease the itch. Be sure to apply it to the skin around the injection, not directly on the site.

  • Is your injection causing pain and itching? You can take an over-the-counter pain reliever–just check with your provider.


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